Cargando…
E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis
Receptor interacting protein kinase 3 (RIP3 or RIPK3), the critical executor of cell programmed necrosis, plays essential roles in maintaining immune responses and appropriate tissue homeostasis. Although the E3 ligases CHIP and PELI1 are reported to promote RIP3 degradation, however, how post-trans...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481267/ https://www.ncbi.nlm.nih.gov/pubmed/33953350 http://dx.doi.org/10.1038/s41418-021-00790-3 |