E3 ligase TRIM25 ubiquitinates RIP3 to inhibit TNF induced cell necrosis

Receptor interacting protein kinase 3 (RIP3 or RIPK3), the critical executor of cell programmed necrosis, plays essential roles in maintaining immune responses and appropriate tissue homeostasis. Although the E3 ligases CHIP and PELI1 are reported to promote RIP3 degradation, however, how post-trans...

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Detalles Bibliográficos
Autores principales: Mei, Pucheng, Xie, Feiyan, Pan, Jiasong, Wang, Sen, Gao, Wenqing, Ge, Rui, Gao, Baocai, Gao, Siqi, Chen, Xiangjun, Wang, Yongming, Wu, Jiaxue, Ding, Chen, Li, Jixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481267/
https://www.ncbi.nlm.nih.gov/pubmed/33953350
http://dx.doi.org/10.1038/s41418-021-00790-3

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