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A general approach to protein folding using thermostable exoshells

In vitro protein folding is a complex process which often results in protein aggregation, low yields and low specific activity. Here we report the use of nanoscale exoshells (tES) to provide complementary nanoenvironments for the folding and release of 12 highly diverse protein substrates ranging fr...

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Detalles Bibliográficos
Autores principales: Sadeghi, Samira, Deshpande, Siddharth, Vallerinteavide Mavelli, Girish, Aksoyoglu, Alphan, Bafna, Jayesh, Winterhalter, Mathias, Kini, R. Manjunatha, Lane, David P., Drum, Chester L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481291/
https://www.ncbi.nlm.nih.gov/pubmed/34588451
http://dx.doi.org/10.1038/s41467-021-25996-4