MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer

Junctional adhesion molecules (JAMs) play a critical role in cell permeability, polarity and migration. JAM-A, a key protein of the JAM family, is altered in a number of conditions including cancer; however, consequences of JAM-A dysregulation on carcinogenesis appear to be tissue dependent and orga...

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Detalles Bibliográficos
Autores principales: Lampis, Andrea, Hahne, Jens C., Gasparini, Pierluigi, Cascione, Luciano, Hedayat, Somaieh, Vlachogiannis, Georgios, Murgia, Claudio, Fontana, Elisa, Edwards, Joanne, Horgan, Paul G., Terracciano, Luigi, Sansom, Owen J., Martins, Carlos D., Kramer-Marek, Gabriela, Croce, Carlo M., Braconi, Chiara, Fassan, Matteo, Valeri, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481293/
https://www.ncbi.nlm.nih.gov/pubmed/34226680
http://dx.doi.org/10.1038/s41418-021-00820-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481293/
https://www.ncbi.nlm.nih.gov/pubmed/34226680
http://dx.doi.org/10.1038/s41418-021-00820-0

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