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Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway

In the present study, we aimed to find the target of Tanshinone IIA (Tan-IIA) in Cholangiocarcinoma by network pharmacology-based prediction and investigate the possible mechanism through experimental verification. In this study, we combined Tan-IIA-specific and Cholangiocarcinoma-specific targets w...

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Detalles Bibliográficos
Autores principales: Liu, Huayuan, Liu, Caiyun, Wang, Mengya, Sun, Dongxu, Zhu, Pengcheng, Zhang, Ping, Tan, Xueying, Shi, Guangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481305/
https://www.ncbi.nlm.nih.gov/pubmed/34588580
http://dx.doi.org/10.1038/s41598-021-98948-z