Repurposing the antibacterial drugs for inhibition of SARS-CoV2-PLpro using molecular docking, MD simulation and binding energy calculation

Papain-like protease (nsp-3; non-structural protein) of novel corona virus is an ideal target for developing drugs as it plays multiple important functions for viral growth and replication. For instance, role of nsp-3 has been recognized in cleavage of viral polyprotein; furthermore, in infected hos...

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Detalles Bibliográficos
Autores principales: Patel, Rohit, Prajapati, Jignesh, Rao, Priyashi, Rawal, Rakesh M., Saraf, Meenu, Goswami, Dweipayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481324/
https://www.ncbi.nlm.nih.gov/pubmed/34591234
http://dx.doi.org/10.1007/s11030-021-10325-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481324/
https://www.ncbi.nlm.nih.gov/pubmed/34591234
http://dx.doi.org/10.1007/s11030-021-10325-0

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