TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A

TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes (FLS). Nowadays, only 20–30% of patients experience remission after the standard of care therapy—antibodies against T...

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Detalles Bibliográficos
Autores principales: Koedderitzsch, Kathrin, Zezina, Ekaterina, Li, Lingzi, Herrmann, Matthias, Biesemann, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481345/
https://www.ncbi.nlm.nih.gov/pubmed/34588517
http://dx.doi.org/10.1038/s41598-021-98651-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481345/
https://www.ncbi.nlm.nih.gov/pubmed/34588517
http://dx.doi.org/10.1038/s41598-021-98651-z

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