Differential regulation of mammalian and avian ATOH1 by E2F1 and its implication for hair cell regeneration in the inner ear

The mammalian inner ear has a limited capacity to regenerate its mechanosensory hair cells. This lack of regenerative capacity underlies the high incidence of age-related hearing loss in humans. In contrast, non-mammalian vertebrates can form new hair cells when damage occurs, a mechanism that depen...

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Detalles Bibliográficos
Autores principales: Gómez-Dorado, Miriam, Daudet, Nicolas, Gale, Jonathan E., Dawson, Sally J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481459/
https://www.ncbi.nlm.nih.gov/pubmed/34588543
http://dx.doi.org/10.1038/s41598-021-98816-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481459/
https://www.ncbi.nlm.nih.gov/pubmed/34588543
http://dx.doi.org/10.1038/s41598-021-98816-w

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