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Establishment of appropriate glaucoma models using dexamethasone or TGFβ2 treated three-dimension (3D) cultured human trabecular meshwork (HTM) cells

To establish appropriate ex vivo models for a glaucomatous trabecular meshwork (TM), two-dimensional (2D) and three-dimensional (3D) cultures of human trabecular meshwork cells (HTM) were prepared in the presence of 250 nM dexamethasone (DEX) or 5 ng/mL TGFβ2, and characterized by the following anal...

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Detalles Bibliográficos
Autores principales: Watanabe, Megumi, Ida, Yosuke, Ohguro, Hiroshi, Ota, Chiaki, Hikage, Fumihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481525/
https://www.ncbi.nlm.nih.gov/pubmed/34588570
http://dx.doi.org/10.1038/s41598-021-98766-3