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Voiding defects in acute radiation cystitis driven by urothelial barrier defect through loss of E-cadherin, ZO-1 and Uroplakin III

Long term-side effects from cancer therapies are a growing health care concern as life expectancy among cancer survivors increases. Damage to the bladder is common in patients treated with radiation therapy for pelvic cancers and can result in radiation (hemorrhagic) cystitis (RC). The disease progr...

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Detalles Bibliográficos
Autores principales: Zwaans, Bernadette M. M., Carabulea, Alexander L., Bartolone, Sarah N., Ward, Elijah P., Chancellor, Michael B., Lamb, Laura E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481534/
https://www.ncbi.nlm.nih.gov/pubmed/34588475
http://dx.doi.org/10.1038/s41598-021-98303-2