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Mapping protein interactions in the active TOM-TIM23 supercomplex

Nuclear-encoded mitochondrial proteins destined for the matrix have to be transported across two membranes. The TOM and TIM23 complexes facilitate the transport of precursor proteins with N-terminal targeting signals into the matrix. During transport, precursors are recognized by the TIM23 complex i...

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Detalles Bibliográficos
Autores principales: Gomkale, Ridhima, Linden, Andreas, Neumann, Piotr, Schendzielorz, Alexander Benjamin, Stoldt, Stefan, Dybkov, Olexandr, Kilisch, Markus, Schulz, Christian, Cruz-Zaragoza, Luis Daniel, Schwappach, Blanche, Ficner, Ralf, Jakobs, Stefan, Urlaub, Henning, Rehling, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481542/
https://www.ncbi.nlm.nih.gov/pubmed/34588454
http://dx.doi.org/10.1038/s41467-021-26016-1