Mosaic Hemagglutinin-Based Whole Inactivated Virus Vaccines Induce Broad Protection Against Influenza B Virus Challenge in Mice

Influenza viruses undergo antigenic changes in the immuno-dominant hemagglutinin (HA) head domain, necessitating annual re-formulation of and re-vaccination with seasonal influenza virus vaccines for continuing protection. We previously synthesized mosaic HA (mHA) proteins of influenza B viruses whi...

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Detalles Bibliográficos
Autores principales: Liu, Yonghong, Strohmeier, Shirin, González-Domínguez, Irene, Tan, Jessica, Simon, Viviana, Krammer, Florian, García-Sastre, Adolfo, Palese, Peter, Sun, Weina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481571/
https://www.ncbi.nlm.nih.gov/pubmed/34603333
http://dx.doi.org/10.3389/fimmu.2021.746447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481571/
https://www.ncbi.nlm.nih.gov/pubmed/34603333
http://dx.doi.org/10.3389/fimmu.2021.746447

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