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NEK7-Mediated Activation of NLRP3 Inflammasome Is Coordinated by Potassium Efflux/Syk/JNK Signaling During Staphylococcus aureus Infection

Staphylococcus aureus (S. aureus) is a foodborne pathogen that causes severe diseases, such as endocarditis, sepsis, and bacteremia. As an important component of innate immune system, the NLR family pyrin domain-containing 3 (NLRP3) inflammasome plays a critical role in defense against pathogen infe...

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Detalles Bibliográficos
Autores principales: Liu, Ruiqing, Liu, Yashan, Liu, Chang, Gao, Aijiao, Wang, Lin, Tang, Huixin, Wu, Qiang, Wang, Xia, Tian, Derun, Qi, Zhi, Shen, Yanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481599/
https://www.ncbi.nlm.nih.gov/pubmed/34603335
http://dx.doi.org/10.3389/fimmu.2021.747370