Platelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling

Phenotypic switch of vascular smooth muscle cells (VSMCs) is important in vascular remodeling which causes hyperplasia and restenosis after intimal injury. Platelets are activated at injured intima and secrete platelet-derived microvesicles (PMVs). Herein, we demonstrated the role of PMVs in VSMC ph...

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Detalles Bibliográficos
Autores principales: Liu, Ji-Ting, Bao, Han, Fan, Yang-Jing, Li, Zi-Tong, Yao, Qing-Ping, Han, Yue, Zhang, Ming-Liang, Jiang, Zong-Lai, Qi, Ying-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481604/
https://www.ncbi.nlm.nih.gov/pubmed/34604241
http://dx.doi.org/10.3389/fcell.2021.744320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481604/
https://www.ncbi.nlm.nih.gov/pubmed/34604241
http://dx.doi.org/10.3389/fcell.2021.744320

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