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Role of BET Proteins in Inflammation and CNS Diseases

Bromodomain and extra-terminal domain (BET) proteins consist of four mammalian members (BRD2, BRD3, BRD4, and BRDT), which play a pivotal role in the transcriptional regulation of the inflammatory response. Dysregulated inflammation is a key pathological process in various CNS disorders through mult...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Yang, Changjun, Candelario-Jalil, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481655/
https://www.ncbi.nlm.nih.gov/pubmed/34604312
http://dx.doi.org/10.3389/fmolb.2021.748449