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β-Hairpin Peptide Mimics Decrease Human Islet Amyloid Polypeptide (hIAPP) Aggregation

Amyloid diseases are degenerative pathologies, highly prevalent today because they are closely related to aging, that have in common the erroneous folding of intrinsically disordered proteins (IDPs) which aggregate and lead to cell death. Type 2 Diabetes involves a peptide called human islet amyloid...

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Detalles Bibliográficos
Autores principales: Lesma, Jacopo, Bizet, Faustine, Berardet, Corentin, Tonali, Nicolo, Pellegrino, Sara, Taverna, Myriam, Khemtemourian, Lucie, Soulier, Jean-Louis, van Heijenoort, Carine, Halgand, Frédéric, Ha-Duong, Tâp, Kaffy, Julia, Ongeri, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481668/
https://www.ncbi.nlm.nih.gov/pubmed/34604227
http://dx.doi.org/10.3389/fcell.2021.729001