Endothelial deletion of PKCδ prevents VEGF inhibition and restores blood flow reperfusion in diabetic ischemic limb

AIMS: Peripheral artery disease is a complication of diabetes leading to critical hindlimb ischemia. Diabetes-induced inhibition of VEGF actions is associated with the activation of protein kinase Cδ (PKCδ). We aim to specifically investigate the role of PKCδ in endothelial cell (EC) function and VE...

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Detalles Bibliográficos
Autores principales: Croteau, Laura, Mercier, Clément, Fafard-Couture, Étienne, Nadeau, Alexandre, Robillard, Stéphanie, Breton, Valérie, Guay, Andréanne, Lizotte, Farah, Despatis, Marc-Antoine, Geraldes, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481738/
https://www.ncbi.nlm.nih.gov/pubmed/33722087
http://dx.doi.org/10.1177/1479164121999033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481738/
https://www.ncbi.nlm.nih.gov/pubmed/33722087
http://dx.doi.org/10.1177/1479164121999033

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