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An Integrative Network Science and Artificial Intelligence Drug Repurposing Approach for Muscle Atrophy in Spaceflight Microgravity

Muscle atrophy is a side effect of several terrestrial diseases which also affects astronauts severely in space missions due to the reduced gravity in spaceflight. An integrative graph-theoretic network-based drug repurposing methodology quantifying the interplay of key gene regulations and protein–...

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Detalles Bibliográficos
Autores principales: Manian, Vidya, Orozco-Sandoval, Jairo, Diaz-Martinez, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481783/
https://www.ncbi.nlm.nih.gov/pubmed/34604234
http://dx.doi.org/10.3389/fcell.2021.732370