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An Integrative Network Science and Artificial Intelligence Drug Repurposing Approach for Muscle Atrophy in Spaceflight Microgravity
Muscle atrophy is a side effect of several terrestrial diseases which also affects astronauts severely in space missions due to the reduced gravity in spaceflight. An integrative graph-theoretic network-based drug repurposing methodology quantifying the interplay of key gene regulations and protein–...
Autores principales: | Manian, Vidya, Orozco-Sandoval, Jairo, Diaz-Martinez, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481783/ https://www.ncbi.nlm.nih.gov/pubmed/34604234 http://dx.doi.org/10.3389/fcell.2021.732370 |
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