Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a fatal disease in which the normal alveolar network is gradually replaced by fibrotic scars. Current evidence suggests that metabolic alterations correlate with myofibroblast activation in IPF. Anlotinib has been proposed to have antifibrotic effects, but the...

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Detalles Bibliográficos
Autores principales: Chen, Weimou, Zhang, Jinming, Zhong, Wenshan, Liu, Yuanyuan, Lu, Ye, Zeng, Zhaojin, Huang, Haohua, Wan, Xuan, Meng, Xiaojing, Zou, Fei, Cai, Shaoxi, Dong, Hangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481786/
https://www.ncbi.nlm.nih.gov/pubmed/34603058
http://dx.doi.org/10.3389/fphar.2021.744826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481786/
https://www.ncbi.nlm.nih.gov/pubmed/34603058
http://dx.doi.org/10.3389/fphar.2021.744826

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