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Anlotinib Inhibits PFKFB3-Driven Glycolysis in Myofibroblasts to Reverse Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a fatal disease in which the normal alveolar network is gradually replaced by fibrotic scars. Current evidence suggests that metabolic alterations correlate with myofibroblast activation in IPF. Anlotinib has been proposed to have antifibrotic effects, but the...
Autores principales: | Chen, Weimou, Zhang, Jinming, Zhong, Wenshan, Liu, Yuanyuan, Lu, Ye, Zeng, Zhaojin, Huang, Haohua, Wan, Xuan, Meng, Xiaojing, Zou, Fei, Cai, Shaoxi, Dong, Hangming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481786/ https://www.ncbi.nlm.nih.gov/pubmed/34603058 http://dx.doi.org/10.3389/fphar.2021.744826 |
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