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Chemoinformatic Study and In vitro Bioevaluation of Tc-99m-Labeled N-Acetyl Neuraminic Acid in C6 Glioma Cells: Potential Role as a Radionuclide Imaging Probe

BACKGROUND: To date, the use of sialic acid that are reported to be elevated during malignancy has been largely unexplored for tumor imaging. The purpose of the present study was to study the modeled stable conformers of n-acetyl neuraminic acid (Neu5Ac) and its radiolabeled conjugate (Tc-99m-Neu5Ac...

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Detalles Bibliográficos
Autores principales: Kumar, Ravi Ranjan, Jaswal, Radhika Rani, Saini, Avneet, Dhawan, Devinder Kumar, Chadha, Vijayta Dani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481855/
https://www.ncbi.nlm.nih.gov/pubmed/34658550
http://dx.doi.org/10.4103/ijnm.ijnm_5_21