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Chemoinformatic Study and In vitro Bioevaluation of Tc-99m-Labeled N-Acetyl Neuraminic Acid in C6 Glioma Cells: Potential Role as a Radionuclide Imaging Probe
BACKGROUND: To date, the use of sialic acid that are reported to be elevated during malignancy has been largely unexplored for tumor imaging. The purpose of the present study was to study the modeled stable conformers of n-acetyl neuraminic acid (Neu5Ac) and its radiolabeled conjugate (Tc-99m-Neu5Ac...
Autores principales: | Kumar, Ravi Ranjan, Jaswal, Radhika Rani, Saini, Avneet, Dhawan, Devinder Kumar, Chadha, Vijayta Dani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481855/ https://www.ncbi.nlm.nih.gov/pubmed/34658550 http://dx.doi.org/10.4103/ijnm.ijnm_5_21 |
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