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Credibility Assessment of a Subject-Specific Mathematical Model of Blood Volume Kinetics for Prediction of Physiological Response to Hemorrhagic Shock and Fluid Resuscitation

Subject-specific mathematical models for prediction of physiological parameters such as blood volume, cardiac output, and blood pressure in response to hemorrhage have been developed. In silico studies using these models may provide an effective tool to generate pre-clinical safety evidence for medi...

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Detalles Bibliográficos
Autores principales: Parvinian, Bahram, Bighamian, Ramin, Scully, Christopher George, Hahn, Jin-Oh, Pathmanathan, Pras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481867/
https://www.ncbi.nlm.nih.gov/pubmed/34603074
http://dx.doi.org/10.3389/fphys.2021.705222