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Credibility Assessment of a Subject-Specific Mathematical Model of Blood Volume Kinetics for Prediction of Physiological Response to Hemorrhagic Shock and Fluid Resuscitation
Subject-specific mathematical models for prediction of physiological parameters such as blood volume, cardiac output, and blood pressure in response to hemorrhage have been developed. In silico studies using these models may provide an effective tool to generate pre-clinical safety evidence for medi...
Autores principales: | Parvinian, Bahram, Bighamian, Ramin, Scully, Christopher George, Hahn, Jin-Oh, Pathmanathan, Pras |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481867/ https://www.ncbi.nlm.nih.gov/pubmed/34603074 http://dx.doi.org/10.3389/fphys.2021.705222 |
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