Rescuing eGFP-Tagged Canine Distemper Virus for 40 Serial Passages Separately in Ribavirin- and Non-Treated Cells: Comparative Analysis of Viral Mutation Profiles

Due to lacking a proofreading mechanism in their RNA-dependent RNA polymerases (RdRp), RNA viruses generally possess high mutation frequencies, making them evolve rapidly to form viral quasispecies during serial passages in cells, especially treated with mutagens, like ribavirin. Canine distemper vi...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Fuxiao, Wang, Ning, Lin, Jiahui, Wang, Qianqian, Huang, Yilan, Zhang, Youming, Shan, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481889/
https://www.ncbi.nlm.nih.gov/pubmed/34604118
http://dx.doi.org/10.3389/fcimb.2021.746926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481889/
https://www.ncbi.nlm.nih.gov/pubmed/34604118
http://dx.doi.org/10.3389/fcimb.2021.746926

Ejemplares similares