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SAW1 is increasingly required to recruit Rad10 as SSA flap-length increases from 20 to 50 bases in single-strand annealing in S. cerevisiae

SAW1 is required by the Rad1-Rad10 nuclease for efficient removal of 3′ non-homologous DNA ends (flaps) formed as intermediates during two modes of double-strand break repair in S. cerevisiae, single-strand annealing (SSA) and synthesis-dependent strand annealing (SDSA). Saw1 was shown in vitro to e...

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Detalles Bibliográficos
Autores principales: Odango, Rowen Jane, Camberos, Juan, Fregoso, Fred Erick, Fischhaber, Paula L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481969/
https://www.ncbi.nlm.nih.gov/pubmed/34622036
http://dx.doi.org/10.1016/j.bbrep.2021.101125