SPT6 loss permits the transdifferentiation of keratinocytes into an intestinal fate that resembles Barrett’s metaplasia

Transient depletion of the transcription elongation factor SPT6 in the keratinocyte has been recently shown to inhibit epidermal differentiation and stratification; instead, they transdifferentiate into a gut-like lineage. We show here that this phenomenon of transdifferentiation recapitulates Barre...

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Detalles Bibliográficos
Autores principales: Vo, Daniella T., Fuller, MacKenzie R., Tindle, Courtney, Anandachar, Mahitha Shree, Das, Soumita, Sahoo, Debashis, Ghosh, Pradipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481972/
https://www.ncbi.nlm.nih.gov/pubmed/34622168
http://dx.doi.org/10.1016/j.isci.2021.103121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481972/
https://www.ncbi.nlm.nih.gov/pubmed/34622168
http://dx.doi.org/10.1016/j.isci.2021.103121

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