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Protocol for preparation and measurement of intracellular and extracellular modified RNA using liquid chromatography-mass spectrometry
About 150 modifications have been identified in RNA species. Besides their regulatory roles in the intracellular gene expression, abundant modified RNA nucleosides are catabolized from RNA and released into extracellular fluids, which can impact extracellular signaling as ligands for receptors. Here...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482036/ https://www.ncbi.nlm.nih.gov/pubmed/34622220 http://dx.doi.org/10.1016/j.xpro.2021.100848 |