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Activity of the Gamma Secretase Inhibitor AL101 in Desmoid Tumors: A Case Report of 2 Adult Cases

Desmoid tumors (aggressive fibromatosis) are soft tissue mesenchymal tumors that can be locally invasive and life-threatening. Depending on the location, these tumors are often unresectable or tend to recur after surgery. To date, there are no approved systemic therapies for desmoid tumors. These tu...

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Detalles Bibliográficos
Autores principales: Chan, David, Kaplan, Jason, Gordon, Gary, Desai, Jayesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482204/
https://www.ncbi.nlm.nih.gov/pubmed/34590610
http://dx.doi.org/10.3390/curroncol28050312