Enzymatically produced piggyBac transposon vectors for efficient non-viral manufacturing of CD19-specific CAR T cells

The piggyBac transposon system provides a non-viral alternative for cost-efficient and simple chimeric antigen receptor (CAR) T cell production. The generation of clinical-grade CAR T cells requires strict adherence to current good manufacturing practice (cGMP) standards. Unfortunately, the high cos...

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Detalles Bibliográficos
Autores principales: Kaštánková, Iva, Štach, Martin, Žižková, Hana, Ptáčková, Pavlína, Šmilauerová, Kristýna, Mucha, Martin, Šroller, Vojtěch, Otáhal, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482285/
https://www.ncbi.nlm.nih.gov/pubmed/34631931
http://dx.doi.org/10.1016/j.omtm.2021.08.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482285/
https://www.ncbi.nlm.nih.gov/pubmed/34631931
http://dx.doi.org/10.1016/j.omtm.2021.08.006

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