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Prenatal inflammation exposure-programmed hypertension exhibits multi-generational inheritance via disrupting DNA methylome

The multi-generation heredity trait of hypertension in human has been reported, but the molecular mechanisms underlying multi-generational inheritance of hypertension remain obscure. Recent evidence shows that prenatal inflammatory exposure (PIE) results in increased incidence of cardiovascular dise...

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Detalles Bibliográficos
Autores principales: Guan, Xiao, Dan, Guo-rong, Yang, Yao, Ji, Yan, Lai, Wen-jing, Wang, Fang-jie, Meng, Meng, Mo, Bang-hui, Huang, Pei, You, Ting-ting, Deng, Ya-fei, Song, Liang, Guo, Wei, Yi, Ping, Yu, Jian-hua, Gao, Yuan, Shou, Wei-nian, Chen, Bing-bo, Deng, You-cai, Li, Xiao-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482360/
https://www.ncbi.nlm.nih.gov/pubmed/34593973
http://dx.doi.org/10.1038/s41401-021-00772-8