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Computational and Experimental Assessments of Magnolol as a Neuroprotective Agent and Utilization of UiO-66(Zr) as Its Drug Delivery System

[Image: see text] The phenolic natural product magnolol exhibits neuroprotective properties through β-amyloid toxicity in PC-12 cells and ameliorative effects against cognitive deficits in a TgCRND8 transgenic mice model. Its bioavailability and blood–brain barrier crossing ability have been signifi...

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Detalles Bibliográficos
Autores principales: Santos, Joshua, Quimque, Mark Tristan, Liman, Rhenz Alfred, Agbay, Jay Carl, Macabeo, Allan Patrick G., Corpuz, Mary Jho-Anne, Wang, Yun-Ming, Lu, Tsai-Te, Lin, Chia-Her, Villaflores, Oliver B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482410/
https://www.ncbi.nlm.nih.gov/pubmed/34604621
http://dx.doi.org/10.1021/acsomega.1c02555