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Influence of pre-analytical sample preparation on drug concentration measurements in peritoneal tissue: an ex-vivo study

OBJECTIVES: Biopsy morphology (surface/depth ratio) and sample processing might affect pharmacological measurements in peritoneal tissue. METHODS: This is an ex-vivo study on inverted bovine urinary bladders (IBUB). We compared cisplatin (CIS) and doxorubicin (DOX) concentration in 81 standardized t...

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Detalles Bibliográficos
Autores principales: Castagna, Arianna, Sautkin, Iaroslav, Weinreich, Frank-Jürgen, Lee, Hannah Heejung, Königsrainer, Alfred, Reymond, Marc André, Nadiradze, Giorgi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482446/
https://www.ncbi.nlm.nih.gov/pubmed/34676286
http://dx.doi.org/10.1515/pp-2020-0151