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Importance of the biomass formulation for cancer metabolic modeling and drug prediction

Genome-scale metabolic reconstructions include all known biochemical reactions occurring in a cell. A typical application is the prediction of potential drug targets for cancer treatment. The precision of these predictions relies on the definition of the objective function. Generally, the biomass re...

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Detalles Bibliográficos
Autores principales: Moscardó García, María, Pacheco, Maria, Bintener, Tamara, Presta, Luana, Sauter, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482493/
https://www.ncbi.nlm.nih.gov/pubmed/34622163
http://dx.doi.org/10.1016/j.isci.2021.103110