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Importance of the biomass formulation for cancer metabolic modeling and drug prediction
Genome-scale metabolic reconstructions include all known biochemical reactions occurring in a cell. A typical application is the prediction of potential drug targets for cancer treatment. The precision of these predictions relies on the definition of the objective function. Generally, the biomass re...
Autores principales: | Moscardó García, María, Pacheco, Maria, Bintener, Tamara, Presta, Luana, Sauter, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482493/ https://www.ncbi.nlm.nih.gov/pubmed/34622163 http://dx.doi.org/10.1016/j.isci.2021.103110 |
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