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Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium

The serine/arginine-rich (SR) family of splicing factors plays important roles in mRNA splicing activation, repression, export, stabilization, and translation. SR-splicing factor 5 (SRSF5) is a glucose-inducible protein that promotes tumor cell growth. However, the functional role of SRSF5 in tissue...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoli, Wang, Ze, Xu, Qing, Chen, Yuhan, Liu, Wen, Zhong, Tong, Li, Hongchang, Quan, Chengshi, Zhang, Lingqiang, Cui, Chun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482499/
https://www.ncbi.nlm.nih.gov/pubmed/34622152
http://dx.doi.org/10.1016/j.isci.2021.103097