Cargando…

Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium

The serine/arginine-rich (SR) family of splicing factors plays important roles in mRNA splicing activation, repression, export, stabilization, and translation. SR-splicing factor 5 (SRSF5) is a glucose-inducible protein that promotes tumor cell growth. However, the functional role of SRSF5 in tissue...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaoli, Wang, Ze, Xu, Qing, Chen, Yuhan, Liu, Wen, Zhong, Tong, Li, Hongchang, Quan, Chengshi, Zhang, Lingqiang, Cui, Chun-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482499/ https://www.ncbi.nlm.nih.gov/pubmed/34622152 http://dx.doi.org/10.1016/j.isci.2021.103097

Ejemplares similares

SRSF1-mediated alternative splicing is required for spermatogenesis
por: Lei, Wen-Long, et al.
Publicado: (2023)

Noncompaction of Ventricular Myocardium Involving the Right Ventricle
por: Saglam, Muzaffer, et al.
Publicado: (2015)

Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects
por: Leung, Carmen, et al.
Publicado: (2021)

Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage
por: Comiskey, Daniel F., et al.
Publicado: (2015)

Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth
por: Chen, Yuhan, et al.
Publicado: (2018)

Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation
por: Zhou, Xuexia, et al.
Publicado: (2014)

Relative strength of 5’ splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA
por: Choi, Namjeong, et al.
Publicado: (2021)

SRSF10 is essential for progenitor spermatogonia expansion by regulating alternative splicing
por: Liu, Wenbo, et al.
Publicado: (2022)

SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance
por: Sheng, Junxiu, et al.
Publicado: (2018)

Oncogenic splicing factor SRSF3 regulates ILF3 alternative splicing to promote cancer cell proliferation and transformation
por: Jia, Rong, et al.
Publicado: (2019)

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells
por: Feng, Shenglei, et al.
Publicado: (2022)

A case report of isolated right ventricular noncompaction with mutation of ACVRL1: a new cause of noncompaction of ventricular myocardium?
por: Yu, Bo, et al.
Publicado: (2023)

Unique echocardiographic features of mitral regurgitation associated with noncompaction of the ventricular myocardium
por: Ali, Sulafa Khalid M
Publicado: (2011)

A Case of Noncompaction of the Ventricular Myocardium Combined with Situs Ambiguous with Polysplenia
por: Cho, Yun-Heyong, et al.
Publicado: (2007)

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
por: Hulse, Richard P., et al.
Publicado: (2016)

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements
por: Do, Dang Vinh, et al.
Publicado: (2018)

Alternative polyadenylation dependent function of splicing factor SRSF3 contributes to cellular senescence
por: Shen, Ting, et al.
Publicado: (2019)

Srsf7 Establishes the Juvenile Transcriptome through Age-Dependent Alternative Splicing in Mice
por: Kadota, Yosuke, et al.
Publicado: (2020)

Srsf7 Establishes the Juvenile Transcriptome through Age-Dependent Alternative Splicing in Mice
por: Kadota, Yosuke, et al.
Publicado: (2020)

Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C
por: Skrdlant, Lindsey, et al.
Publicado: (2016)

SRSF3 Promotes Angiogenesis in Colorectal Cancer by Splicing SRF
por: Chen, Yinshuang, et al.
Publicado: (2022)

Titin Circular RNAs Create a Back-Splice Motif Essential for SRSF10 Splicing
por: Tijsen, Anke J., et al.
Publicado: (2021)

Splicing factor SRSF6 mediates pleural fibrosis
por: Liang, Li-Mei, et al.
Publicado: (2021)

Splicing factor SRSF2-centric gene regulation
por: Li, Kun, et al.
Publicado: (2021)

Targeting Splicing Factor SRSF6 for Cancer Therapy
por: She, Wenting, et al.
Publicado: (2021)

Isolated Noncompacted Myocardium in an Elderly Patient
por: de Paula Miranda, Eduardo, et al.
Publicado: (2008)

SRSF2 is required for mRNA splicing during spermatogenesis
por: Lei, Wen-Long, et al.
Publicado: (2023)

Genome-wide analysis of SRSF10-regulated alternative splicing by deep sequencing of chicken transcriptome
por: Zhou, Xuexia, et al.
Publicado: (2014)

SRSF6 balances mitochondrial-driven innate immune outcomes through alternative splicing of BAX
por: Wagner, Allison R, et al.
Publicado: (2022)

RNA binding protein 24 deletion disrupts global alternative splicing and causes dilated cardiomyopathy
por: Liu, Jing, et al.
Publicado: (2018)

BAF57/SMARCE1 Interacting with Splicing Factor SRSF1 Regulates Mechanical Stress-Induced Alternative Splicing of Cyclin D1
por: Feng, Jianguo, et al.
Publicado: (2021)

The Splicing Factor SRSF1 as a Marker for Endothelial Senescence
por: Blanco, Francisco Javier, et al.
Publicado: (2012)

Splicing factor SRSF6 promotes hyperplasia of sensitized skin
por: Jensen, Mads A., et al.
Publicado: (2014)

HIV-1 transcription is regulated by splicing factor SRSF1
por: Paz, Sean, et al.
Publicado: (2014)

A Case of Severe Left-Ventricular Noncompaction Associated with Splicing Altering Variant in the FHOD3 Gene
por: Myasnikov, Roman, et al.
Publicado: (2022)

Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis
por: Gabriel, Maude, et al.
Publicado: (2015)

Splicing factor SRSF1 promotes breast cancer progression via oncogenic splice switching of PTPMT1
por: Du, Jun-Xian, et al.
Publicado: (2021)

LncRNA CRNDE attenuates chemoresistance in gastric cancer via SRSF6-regulated alternative splicing of PICALM
por: Zhang, Feifei, et al.
Publicado: (2021)

CircRPAP2 regulates the alternative splicing of PTK2 by binding to SRSF1 in breast cancer
por: Yu, Yunhe, et al.
Publicado: (2022)

SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence
por: Choi, Namjeong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bd0qckidfrq4e00j40uv6lrcp7