Limited TCR repertoire and ENTPD1 dysregulation mark late-stage COVID-19

T cell exhaustion and dysfunction are hallmarks of severe COVID-19. To gain insights into the pathways underlying these alterations, we performed a comprehensive transcriptome analysis of peripheral-blood-mononuclear-cells (PBMCs), spleen, lung, kidney, liver, and heart obtained at autopsy from COVI...

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Detalles Bibliográficos
Autores principales: Wang, Na, Vuerich, Marta, Kalbasi, Ahmadreza, Graham, Jonathon J., Csizmadia, Eva, Manickas-Hill, Zachary James, Woolley, Ann, David, Clement, Miller, Eric M., Gorman, Kara, Hecht, Jonathan L., Shaefi, Shahzad, Robson, Simon C., Longhi, Maria Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482538/
https://www.ncbi.nlm.nih.gov/pubmed/34608452
http://dx.doi.org/10.1016/j.isci.2021.103205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482538/
https://www.ncbi.nlm.nih.gov/pubmed/34608452
http://dx.doi.org/10.1016/j.isci.2021.103205

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