The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar

BACKGROUND: Contrasting with zebrafish, retinal regeneration from Müller cells (MCs) is largely limited in mammals, where they undergo reactive gliosis that consist of a hypertrophic response and ultimately results in vision loss. Transforming growth factor β (TGFβ) is essential for wound healing, i...

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Detalles Bibliográficos
Autores principales: Conedera, Federica Maria, Pousa, Ana Maria Quintela, Mercader, Nadia, Tschopp, Markus, Enzmann, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482586/
https://www.ncbi.nlm.nih.gov/pubmed/34593012
http://dx.doi.org/10.1186/s13024-021-00482-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482586/
https://www.ncbi.nlm.nih.gov/pubmed/34593012
http://dx.doi.org/10.1186/s13024-021-00482-z

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