Targeting INMT and interrupting its methylation pathway for the treatment of castration resistant prostate cancer

BACKGROUND: Castration-resistant prostate cancer (CRPC) is associated with a very poor prognosis, and the treatment of which remains a serious clinical challenge. METHODS: RNA-seq, qPCR, western blot and immunohistochemistry were employed to identify and confirm the high expression of indolethylamin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Shangwei, Jeong, Ji-Hak, Huang, Changhao, Chen, Xueyan, Dickinson, Shohreh Iravani, Dhillon, Jasreman, Yang, Li, Luo, Jun-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482636/
https://www.ncbi.nlm.nih.gov/pubmed/34587977
http://dx.doi.org/10.1186/s13046-021-02109-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482636/
https://www.ncbi.nlm.nih.gov/pubmed/34587977
http://dx.doi.org/10.1186/s13046-021-02109-z

Ejemplares similares