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Targeting INMT and interrupting its methylation pathway for the treatment of castration resistant prostate cancer

BACKGROUND: Castration-resistant prostate cancer (CRPC) is associated with a very poor prognosis, and the treatment of which remains a serious clinical challenge. METHODS: RNA-seq, qPCR, western blot and immunohistochemistry were employed to identify and confirm the high expression of indolethylamin...

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Detalles Bibliográficos
Autores principales:	Zhong, Shangwei, Jeong, Ji-Hak, Huang, Changhao, Chen, Xueyan, Dickinson, Shohreh Iravani, Dhillon, Jasreman, Yang, Li, Luo, Jun-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482636/ https://www.ncbi.nlm.nih.gov/pubmed/34587977 http://dx.doi.org/10.1186/s13046-021-02109-z

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