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Hyperglycemia compromises the ischemia-provoked dedifferentiation of cerebral pericytes through p21–SOX2 signaling in high-fat diet-induced murine model

AIM: Diabetes-related cerebral small vessel disease (CSVD) causes neurological deficits. Patients with diabetes showed pericyte loss as a hallmark of retinopathy. Cerebral pericytes, which densely localize around brain capillaries, are quiescent stem cells regulating regeneration of brain and may ha...

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Detalles Bibliográficos
Autores principales: Wang, Hao-Kuang, Huang, Chih-Yuan, Chen, Yun-Wen, Sun, Yuan-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482726/
https://www.ncbi.nlm.nih.gov/pubmed/33557613
http://dx.doi.org/10.1177/1479164121990641