Cargando…
Hyperglycemia compromises the ischemia-provoked dedifferentiation of cerebral pericytes through p21–SOX2 signaling in high-fat diet-induced murine model
AIM: Diabetes-related cerebral small vessel disease (CSVD) causes neurological deficits. Patients with diabetes showed pericyte loss as a hallmark of retinopathy. Cerebral pericytes, which densely localize around brain capillaries, are quiescent stem cells regulating regeneration of brain and may ha...
Autores principales: | Wang, Hao-Kuang, Huang, Chih-Yuan, Chen, Yun-Wen, Sun, Yuan-Ting |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482726/ https://www.ncbi.nlm.nih.gov/pubmed/33557613 http://dx.doi.org/10.1177/1479164121990641 |
Ejemplares similares
-
Pericyte Bridges in Homeostasis and Hyperglycemia
por: Corliss, Bruce A., et al.
Publicado: (2020) -
Development of an oncogenic dedifferentiation SOX signature with prognostic significance in hepatocellular carcinoma
por: Li, Mei-Mei, et al.
Publicado: (2019) -
Protective Effect of Topiramate on Hyperglycemia-Induced Cerebral Oxidative Stress, Pericyte Loss and Learning Behavior in Diabetic Mice
por: Price, Tulin O., et al.
Publicado: (2015) -
Pericyte protection by edaravone after tissue plasminogen activator treatment in rat cerebral ischemia
por: Deguchi, Kentaro, et al.
Publicado: (2014) -
The effect of hyperglycemia on lipid peroxidation in the global cerebral ischemia of the rat.
por: Roh, J. K., et al.
Publicado: (1992)