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Roles of vascular endothelial and smooth muscle cells in the vasculoprotective effect of insulin in a mouse model of restenosis

BACKGROUND: Insulin exerts vasculoprotective effects on endothelial cells (ECs) and growth-promoting effects on vascular smooth muscle cells (SMCs) in vitro, and suppresses neointimal growth in vivo. Here we determined the role of ECs and SMCs in the effect of insulin on neointimal growth. METHODS:...

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Detalles Bibliográficos
Autores principales: Mori, Yusaku, Gonzalez Medina, Marel, Liu, Zhiwei, Guo, June, Dingwell, Luke S, Chiang, Simon, Kahn, Carl Ronald, Husain, Mansoor, Giacca, Adria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482728/
https://www.ncbi.nlm.nih.gov/pubmed/34190643
http://dx.doi.org/10.1177/14791641211027324