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Roles of vascular endothelial and smooth muscle cells in the vasculoprotective effect of insulin in a mouse model of restenosis
BACKGROUND: Insulin exerts vasculoprotective effects on endothelial cells (ECs) and growth-promoting effects on vascular smooth muscle cells (SMCs) in vitro, and suppresses neointimal growth in vivo. Here we determined the role of ECs and SMCs in the effect of insulin on neointimal growth. METHODS:...
Autores principales: | Mori, Yusaku, Gonzalez Medina, Marel, Liu, Zhiwei, Guo, June, Dingwell, Luke S, Chiang, Simon, Kahn, Carl Ronald, Husain, Mansoor, Giacca, Adria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482728/ https://www.ncbi.nlm.nih.gov/pubmed/34190643 http://dx.doi.org/10.1177/14791641211027324 |
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