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Design, Synthesis, and In Vitro and In Vivo Evaluation of Novel Fluconazole-Based Compounds with Promising Antifungal Activities

[Image: see text] Demand has arisen for developing new azole antifungal agents with the growth of the resistant rate of infective fungal species to current azole antifungals in recent years. Accordingly, the present study reports the synthesis of novel fluconazole (FLC) analogues bearing urea functi...

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Detalles Bibliográficos
Autores principales: Shafiei, Mohammad, Toreyhi, Hossein, Firoozpour, Loghman, Akbarzadeh, Tahmineh, Amini, Mohsen, Hosseinzadeh, Elaheh, Hashemzadeh, Mehrnoosh, Peyton, Lee, Lotfali, Ensieh, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482776/
https://www.ncbi.nlm.nih.gov/pubmed/34604679
http://dx.doi.org/10.1021/acsomega.1c04016