Cargando…

Synthesis of 12β-Methyl-18-nor-bile Acids

[Image: see text] Decoupling the roles of the farnesoid X nuclear receptor and Takeda G-protein-coupled bile acid receptor 5 is essential for the development of novel bile acid therapeutics targeting metabolic and neurodegenerative diseases. Herein, we describe the synthesis of 12β-methyl-18-nor-bil...

Descripción completa

Detalles Bibliográficos
Autores principales: Luxenburger, Andreas, Harris, Lawrence D., Ure, Elizabeth M., Landaeta Aponte, Roselis A., Woolhouse, Anthony D., Cameron, Scott A., Ling, Chris D., Piltz, Ross O., Lewis, Andrew R., Gainsford, Graeme J., Weymouth-Wilson, Alex, Furneaux, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482778/
https://www.ncbi.nlm.nih.gov/pubmed/34604682
http://dx.doi.org/10.1021/acsomega.1c04199