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Synthesis of 12β-Methyl-18-nor-bile Acids
[Image: see text] Decoupling the roles of the farnesoid X nuclear receptor and Takeda G-protein-coupled bile acid receptor 5 is essential for the development of novel bile acid therapeutics targeting metabolic and neurodegenerative diseases. Herein, we describe the synthesis of 12β-methyl-18-nor-bil...
Autores principales: | Luxenburger, Andreas, Harris, Lawrence D., Ure, Elizabeth M., Landaeta Aponte, Roselis A., Woolhouse, Anthony D., Cameron, Scott A., Ling, Chris D., Piltz, Ross O., Lewis, Andrew R., Gainsford, Graeme J., Weymouth-Wilson, Alex, Furneaux, Richard H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482778/ https://www.ncbi.nlm.nih.gov/pubmed/34604682 http://dx.doi.org/10.1021/acsomega.1c04199 |
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