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O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells

Pituitary adenomas have a staggering 16.7% lifetime prevalence and can be devastating in many patients because of profound endocrine and neurologic dysfunction. To date, no clear genomic or epigenomic markers correlate with their onset or severity. Herein, we investigate the impact of the O-GlcNAc p...

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Detalles Bibliográficos
Autores principales: Massman, Logan J, Pereckas, Michael, Zwagerman, Nathan T, Olivier-Van Stichelen, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482966/
https://www.ncbi.nlm.nih.gov/pubmed/34418053
http://dx.doi.org/10.1210/endocr/bqab178